How to make an AI-Driven Culture Transformation with Moderna’s Head of AI, Brice Challamel

Beyond The Prompt - How to use AI in your company

In this episode, Brice Challamel, Head of AI Products and Platforms at Moderna, pulls back the curtain on how AI is transforming not just workflows but entire organizational cultures. Brice introduces the concept of the AI "catalyst" - a role focused on accelerating safe, effective change - while sharing practical strategies for fostering widespread AI adoption.
Drawing on examples from his leadership at Moderna, Brice explains why it's reckless not to integrate AI into your processes, how to avoid outdated approaches (what he calls "Fred-like behavior") that hold organizations back, and why every individual in a company should think of themselves as a five-person team, augmented by AI.
This episode is a masterclass in how to lead through change, prioritize high-impact innovation, and rethink leadership in the age of AI.

Key Takeaways:

• Catalysts drive AI transformation – Learn how Brice's 'catalyst' approach sparks cultural and technological shifts in organizations.
• AI champions fuel innovation – Discover how Moderna’s Generative AI Champions Team amplifies AI adoption and engagement.
• Augment, don’t replace – Brice explains why the goal is not to replace humans but to enhance their capabilities.
• Outdated habits are out – Embrace modern tools and innovative methodologies to stay ahead.
• Start with ‘Why’ – Understand the importance of anchoring AI initiatives to purpose-driven objectives for lasting success.

Moderna's website: Pioneering mRNA technology - Moderna

00:00 Introduction to Brice Challamel and His Role at Moderna
00:45 What It Means to Be an AI Catalyst
02:30 Leadership in the AI Era: Moving Beyond Traditional Hierarchies
06:10 Avoiding "Fred-like Behavior" in a Modern Workplace
10:20 Augmenting Human Potential: The Five-Person AI Team
14:50 How Moderna Manages 700+ GPTs Safely and Efficiently
20:30 Democratizing AI: Why It's a Utility for Every Employee
27:15 Using AI to Transform Personal and Professional Growth
32:40 Frameworks for Incident Management in AI Integration
39:15 AI’s Role in Healthcare, Radiology, and Beyond
43:30 The Generative AI Champions Team: GCAT in Action
50:00 The Future of Work: Collaboration and Culture with AI
01:03:27 Reflections on AI Adoption and Leadership Insights
📜 Read the transcript for this episode: Transcript of How to make an AI-Driven Culture Transformation with Moderna’s Head of AI, Brice Challamel |

For more prompts, tips, and AI tools. Check out our website: https://www.beyondtheprompt.ai/ or follow Jeremy or Henrik on Linkedin:

Henrik: https://www.linkedin.com/in/werdelin
Jeremy: https://www.linkedin.com/in/jeremyutley

Show edited by Emma Cecilie Jensen.