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The Krebs Cycle
Manage episode 444513130 series 2770060
Contenido proporcionado por MedSchoolCoach. Todo el contenido del podcast, incluidos episodios, gráficos y descripciones de podcast, lo carga y proporciona directamente MedSchoolCoach o su socio de plataforma de podcast. Si cree que alguien está utilizando su trabajo protegido por derechos de autor sin su permiso, puede seguir el proceso descrito aquí https://es.player.fm/legal.
One of the most fundamental biochemical processes is the Krebs cycle. This metabolic pathway plays a critical role in both the Chem Phys and Bio/Biochem sections of the MCAT, so understanding it is key.
In this episode, our guest host, Alex Starks, walks us through the transformation of pyruvate into acetyl CoA via the Pyruvate Dehydrogenase Complex (PDC). We’ll explore how thioester bonds help transfer energy within the cycle, how acetyl CoA combines with oxaloacetate to form citrate, the difference between enzymes like synthetases and synthases, and how GTP is produced. We’ll also make connections to the electron transport chain and discuss how the TCA cycle influences blood pH through CO2 production.
Visit medschoolcoach.com for more help with the MCAT.
Jump into the conversation:
(00:00) Intro
(01:05) Recap of glycolysis and pyruvate
(02:45) Pyruvate dehydrogenase complex (PDC)
(03:40) Role of acetyl CoA in the Krebs cycle
(05:37) How citrate is formed
(07:17) How isocitrate is formed
(10:00) How alpha-ketoglutarate is formed
(13:42) How succinate and GTP are formed
(16:28) How succinate, fumarate and oxaloacetate are formed
(18:23) Fumarate converted to malate
(21:53) Recap of the Krebs cycle and ATP yield
(25:00) Regulation of the Krebs cycle
(26:16) Quiz
184 episodios
Compartir
Manage episode 444513130 series 2770060
Contenido proporcionado por MedSchoolCoach. Todo el contenido del podcast, incluidos episodios, gráficos y descripciones de podcast, lo carga y proporciona directamente MedSchoolCoach o su socio de plataforma de podcast. Si cree que alguien está utilizando su trabajo protegido por derechos de autor sin su permiso, puede seguir el proceso descrito aquí https://es.player.fm/legal.
One of the most fundamental biochemical processes is the Krebs cycle. This metabolic pathway plays a critical role in both the Chem Phys and Bio/Biochem sections of the MCAT, so understanding it is key.
In this episode, our guest host, Alex Starks, walks us through the transformation of pyruvate into acetyl CoA via the Pyruvate Dehydrogenase Complex (PDC). We’ll explore how thioester bonds help transfer energy within the cycle, how acetyl CoA combines with oxaloacetate to form citrate, the difference between enzymes like synthetases and synthases, and how GTP is produced. We’ll also make connections to the electron transport chain and discuss how the TCA cycle influences blood pH through CO2 production.
Visit medschoolcoach.com for more help with the MCAT.
Jump into the conversation:
(00:00) Intro
(01:05) Recap of glycolysis and pyruvate
(02:45) Pyruvate dehydrogenase complex (PDC)
(03:40) Role of acetyl CoA in the Krebs cycle
(05:37) How citrate is formed
(07:17) How isocitrate is formed
(10:00) How alpha-ketoglutarate is formed
(13:42) How succinate and GTP are formed
(16:28) How succinate, fumarate and oxaloacetate are formed
(18:23) Fumarate converted to malate
(21:53) Recap of the Krebs cycle and ATP yield
(25:00) Regulation of the Krebs cycle
(26:16) Quiz
184 episodios
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Similar a MCAT Basics (from MedSchoolCoach)
The BMJ brings you interviews with the people who are shaping medicine and science around the world.
…
continue reading
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Emergency Medicine Cases – Where the Experts Keep You in the Know. For show notes, quizzes, videos and more learning tools please visit emergencymedicinecases.com
…
continue reading
Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
…
continue reading
Science Friction has a new series: Cooked. We dig into food science pickles. Why are studies showing that ice cream could be good for you? Do we really need as many electrolytes as the internet says? And why are people feeling good on the carnivore diet? Nutrition and food scientist Dr Emma Beckett takes us through what the evidence says about food categories and ingredients like meat, dairy and salt — and unpick why nutrition studies can be so conflicting and confusing. Airs Wednesday 11:30 ...
…
continue reading
We humans could have a bright future ahead of us that lasts billions of years. But we have to survive the next 200 years first. Join Josh Clark of Stuff You Should Know for a 10-episode deep dive that explores the future of humanity and finds dangers we have never encountered before lurking just ahead. And if we humans are alone in the universe, if we don't survive intelligent life dies out with us too.
…
continue reading
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…
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Help me fill in the blanks of the practice of ED Critical Care. In this podcast, we discuss all things related to the crashing, critically ill patient in the Emergency Department. Find the show notes at emcrit.org.
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