Breakthroughs podcast

#Medicine #Fitness #Feinberg School Of Medicine #Northwestern University Feinberg School of Medicine #On Covid19

18:09

HR is no longer just about managing people—it’s about shaping the future of work. Jens Baier, BCG’s HR transformation expert, discusses how AI and shifting employee expectations are forcing companies to rethink talent strategies. From re-recruiting to upskilling employees, HR must adapt to a rapidly changing landscape. Learn More: Jens Baier: https://on.bcg.com/41ca7Gv BCG on People Strategy: https://on.bcg.com/3QtAjro Decoding Global Talent: https://on.bcg.com/4gUC4IT…

Breakthroughs

Series en casa•Feed

Breakthroughs is a podcast about groundbreaking research and the scientists leading these discoveries at Northwestern University Feinberg School of Medicine. We are driven by our mission to transform the practice of medicine and profoundly impact human health beyond the individual patient. We believe better answers only come from discovery.

113 episodios

Breakthroughs

17 subscribers

updated hace un día

Series en casa•Feed

113 episodios

#Medicine #Fitness #Feinberg School Of Medicine #Northwestern University Feinberg School of Medicine #On Covid19

Todos los episodios

Breakthroughs

1
How Alzheimer’s Drugs Work with David Gate, PhD 14:44

hace 1 day14:44

14:44

A Northwestern Medicine study published in Nature Medicine, used a new technique called spatial transcriptomics to examine the brain’s response to Alzheimer's therapies, revealing new molecular targets that could enhance the effectiveness of current therapies and not just slow the disease, but potentially improve patient outcomes. David Gate, PhD, assistant professor of Neurology in the Ken and Ruth Davee Department of Neurology and director of the Abrams Research Center on Neurogenomics, led this research.…

Breakthroughs

1
Intervening Earlier in Mental Healthcare for Kids with Lauren Wakschlag, PhD 24:49

hace 5 días24:49

24:49

A new $11.7 million award from the National Institute of Mental Health aims to help Northwestern Medicine investigators move the dial on the youth mental health crisis by targeting early warning signs of mental health risk in toddlers, rather than waiting until diagnosable and severe conditions are present later in childhood. In this episode, Lauren Wakschlag, PhD, who is co-leading this grant, explains how the team will implement evidence-based developmental decision tools to determine “when to worry” about young children's mental health.…

Breakthroughs

1
Advancing Ovarian Health from Fertility to Lifespan with Francesca Duncan, PhD 25:40

hace 19 días25:40

25:40

Women are living longer, healthier lives, but ovarian aging still impacts fertility and hormone production as it always has. In this episode, Francesca Duncan, PhD, discusses novel research into maintaining ovarian function, longer. This work could someday help prevent or slow down age-related changes to the ovaries, offering hope for better health as women age.…

Breakthroughs

1
Pursuing Precision Medicine for Rare Diseases with Gemma Carvill, PhD 26:10

hace 5 weeks26:10

26:10

Scientists from Northwestern Medicine, the Broad Institute of MIT and Harvard have uncovered the first rare genetic disorder linked to a long non-coding RNA gene. In this episode, Gemma Carvill, PhD, explains how this discovery, published in The New England Journal of Medicine , came to be and the critical roles non-coding regions of the genome may have in human health.…

Breakthroughs

1
Investigating the Health Impact of Incarceration with Linda Teplin, PhD 18:55

hace 13 weeks18:55

18:55

With a new $20 million grant from the National Institute on Aging, Northwestern investigator, Linda Teplin, PhD, is extending the work of the Northwestern Juvenile Project to study the long-term consequences of incarceration on age-related conditions, including Alzheimer's and other age-related diseases. This project is the only large-scale longitudinal study of its kind tracking health and outcomes of detained juveniles in the years following their release.…

Breakthroughs

1
Studying Social Networks to Address Health Inequities with Michelle Birkett, PhD 24:23

hace 15 weeks24:23

24:23

Understanding the systemic drivers of health disparities within marginalized populations is complex. In this episode, Michelle Birkett, PhD, explains how she uses network and quantitative methodologies to study the health of marginalized populations, particularly sexual and gender minority youth. She also discusses her new center, the Center for Computational and Social Sciences in Health, and the importance of transdisciplinary research.…

Breakthroughs

1
Emerging Drug Targets in Parkinson's Disease with Joe Mazzulli, PhD 28:08

hace 18 weeks28:08

28:08

Nearly one million people in the U.S. are living with Parkinson's disease, a condition for which there is still no known cause or cure. Joseph Mazzulli, PhD, has led two recent studies published in Neuron and Nature Communications uncovering previously unknown cellular mechanisms driving the disease. These studies highlight the potential for new therapeutic targets, including restoring neuronal function for patients with Parkinson's and other neurodegenerative diseases.…

Breakthroughs

1
New Insights into Cellular Metabolism with Issam Ben-Sahra, PhD 18:14

hace 20 weeks18:14

18:14

New research from the lab of Issam Ben-Sahra, PhD, could rewrite textbooks on our understanding of cellular metabolism and potentially identify new targets for cancer and metabolic diseases such as obesity. The discovery, published in the journal Science, has been praised for its rigorous simplicity and underscores the importance of understanding the molecular mechanisms that underlie specific biological processes.…

Breakthroughs

1
Understanding Gut Microbiome Science with Jeffrey Gordon, MD 35:30

hace 22 weeks35:30

35:30

Jeffrey Gordon, MD, often called “the father of microbiome research,” is the 2024 recipient of the Mechthild Esser Nemmers Prize in Medical Science. In this episode, Gordon discusses the impacts of his long career in gut microbiome research, which has profoundly transformed our understanding of human health. Specifically, he shares the evolution of groundbreaking approaches to treating malnutrition and childhood undernutrition with microbiota-targeted therapies.…

Breakthroughs

1
Overcoming Hormone Therapy Resistance in Prostate Cancer with Sarki Abdulkadir, MD, PhD 23:03

hace 25 weeks23:03

23:03

The MYC oncogene is notorious in the cancer research world because it is implicated in many advanced or aggressive cancers such as treatment-resistant prostate cancer. In this episode, Sarki Abdulkadir, MD, PhD, shares how his team bucked the conventional notion that the MYC gene is “undruggable” and uncovered a handful of compounds that block MYC gene activity, making prostate cancer tumors sensitive to hormone therapy and opening up a potential new therapeutic target for treatment-resistant prostate cancer.…

Breakthroughs

1
How to Measure Biological Age with John Wilkins, MD 21:27

hace 33 weeks21:27

21:27

A team of Northwestern Medicine scientists are conducting a new longitudinal cross-sectional study to investigate why some people see to age faster than others. In this episode, John Wilkins, MD, associate director of the Human Longevity Laboratory at the Potocsnak Longevity Institute, shares details of the study, which will eventually include a variety of interventions aimed at slowing down the aging process.…

Breakthroughs

1
A Compelling New Lupus Discovery with Jaehyuk Choi, MD, PhD 20:10

hace 34 weeks20:10

20:10

Northwestern Medicine physician-scientist Jaehyuk Choi, MD, PhD joins the show again to discuss another breakthrough. This time for lupus, a chronic autoimmune condition affecting 300,000 Americans that can cause inflammation in many body parts, including joints, skin, kidneys, blood cells, brain, heart and lungs. Findings by Choi and his lab members not only elucidate the underlying mechanisms of lupus but also suggest potential therapeutic strategies.…

Breakthroughs

1
Uncovering Insights into Cancer and Alzheimer's with Marcus Peter, PhD 27:36

hace 42 weeks27:36

27:36

For decades, Marcus Peter, PhD, has drilled into an area of research focused on cell death and the roles of toxic and protective short RNAs, with the goal of developing a novel form of cancer treatment. Now, this same line of research has led Peter’s team to uncover new insights into the cause of Alzheimer's disease. In this episode, Peter explains his pioneering work in investigating RNA interference in diseases and explains how his lab’s latest novel discovery may have relevance to an array of neurodegenerative diseases beyond Alzheimer’s.…

Breakthroughs

1
The Evolution of Digital Pathology with Lee Cooper, PhD 20:11

hace 44 weeks20:11

20:11

New advances in digital pathology are revolutionizing the analysis of disease, paving the way for greater accuracy and efficiency when it comes to diagnostics, predicting outcomes and treatment. In this episode, Lee Cooper, PhD, discusses the future of digital and computational pathology and his research on machine learning and pathology, including a recent study published in Nature Medicine on using AI in predicting clinical outcomes for breast cancer patients.…

Breakthroughs

1
Driving Innovations in Biostatistics with Denise Scholtens, PhD 23:33

hace 46 weeks23:33