Interesting article: do children with cancer have an underlying gene abnormality?

Understanding Childhood Cancer With Dr Geoff

#Science #Childhood Cancer #Dr Geoff

31:01

National Geographic photographer and conservationist Jaime Rojo has spent decades capturing the beauty and fragility of the monarch butterfly. Their epic migration is one of nature’s most breathtaking spectacles, but their survival is under threat. In this episode, Jaime shares how his passion for photography and conservation led him to document the monarchs’ journey. He and host Brian Lowery discuss the deeper story behind his award-winning images, one about resilience, connection, and the urgent need to protect our natural world. See Jaime's story on the monarch butterflies at his website: rojovisuals.com , and follow Brian Lowery at knowwhatyousee.com .…

hace 9 años 35:47

MP3•Episodio en casa

Parents always ask why their child developed cancer. They ask if it is genetic, meaning is it something hereditary, or some abnormality in the DNA that the child was born with. In this episode I discuss a recent paper that examined this question. Link to Patreon

Hosted on Acast. See acast.com/privacy for more information.

81 episodios

Interesting article: do children with cancer have an underlying gene abnormality?

Understanding Childhood Cancer With Dr Geoff

11 subscribers

published hace 9 años

MP3•Episodio en casa

Hosted on Acast. See acast.com/privacy for more information.

81 episodios

#Science #Childhood Cancer #Dr Geoff

Todos los episodios

1
CAR T-cells, Interview with Dr Caroline Bateman 45:55

hace 3 years45:55

45:55

CAR T-cell therapy is an exciting new treatment for acute leukaemia. In this episode, Dr Geoff interviews his colleague Dr Caroline Bateman about CAR T-cells and introducing the treatment option to her unit. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
"S" is for "Special" : Stage MS Neuroblastoma (also called Stage IVS, 4S) 24:26

hace 4 years24:26

24:26

There is a special subtype of neuroblastoma seen in very young children, with spread of disease throughout the body, but which needs a very different approach to treatment compared to older children with metastatic disease. This episode explains the features of this stage MS neuroblastoma, the early problems, and the treatment used. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.…

1
Where did my child's immune system go? 44:44

hace 4 years44:44

44:44

Childhood cancer treatment leads to severe impairment of the ability to fight infections. This episode explains what immune suppression means, what causes it, and the problems that result. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
Update re the future of rock and roll.... CAR T-cells 39:46

hace 4 years39:46

39:46

A few years ago I described CAR T-cells, but they weren't available for routine use. I now update things, with the very important news about CAR T-cell therapy now becoming available. There is also an interview with Dr Caroline Bateman re this subject in another episode. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.…

1
Blood Cultures 22:13

hace 4 years22:13

22:13

We take a lot of blood samples looking for infection in the bloodstream. This episode explains what blood cultures are all about. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
PRISM, Molecular Profiling, and Informed Consent 56:12

hace 4 years56:12

56:12

A number of countries have research studies where childhood cancers are analysed in great detail, testing all the DNA in something called 'molecular profiling'. The national Australian study of this is called PRISM, and it is a very exciting project. This episode explains a molecular profiling project and covers issues of obtaining informed consent from parents and patients as well. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.…

1
The MEK inhibitors: trametinib and selumetinib 41:14

hace 4 years41:14

41:14

The MEK inhibitors are a newer class of drug, and include trametinib, selumetinib and others. They have an important role in paediatric oncology, particularly in glioma treatment and in neurofibromatosis. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
The needle in the haystack: Minimal Residual Disease 42:05

hace 4 years42:05

42:05

Sophisticated techniques can detect one cancer cell amongst a million normal cells. This episode describes these methods and how they are used in treatment. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
DIPG: to biopsy or not to biopsy 13:37

hace 4 years13:37

13:37

For many years we didn't biopsy the tumour when the scans suggested that the tumour was a DIPG. This episode explains why that has changed, and the emerging role of biopsy. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
DIPG: what do these letters stand for? 19:55

hace 8 years19:55

19:55

DIPG is a type of brain tumor which occurs in children. This episode explains what the letters mean. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
Chemotherapy 7: Ifosfamide 22:51

hace 8 years22:51

22:51

Ifosfamide is another chemotherapy drug, used particularly in certain sarcomas and certain patients with leukaemia. This episode explains how it is given, and common and rare side effects. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
Why does my child need a heart test? Echo's and ECG's. 16:42

hace 8 years16:42

16:42

We often need to evaluate heart function during chemotherapy. This episode explains what the tests are, and why we need to do them. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
Highlights of ASCO: Two transplants for neuroblastoma?? 30:12

hace 9 years30:12

30:12

At the American Society of Clinical Oncology meeting in June 2016, a study was presented looking at using two autologous bone marrow transplants in neuroblastoma. The results were exciting.... Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

1
"A Selfless Act": my reading of an article on clinical trials in childhood cancer. 17:52

hace 9 years17:52

17:52

In this episode I read out for you an article written by Dr Susan Cohn from the University of Chicago. Dr Cohn is an eminent paediatric oncologist, and a world expert on children's cancer trials, particularly in neuroblastoma. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.…

1
Residents, fellows, registrars; who are all these doctors? 31:49

hace 9 years31:49