Science Changing Life podcast

25:09

What if the key to detecting the next pandemic was hidden in our wastewater? By analyzing pathogens found in sewage, scientists can track the spread of infections before they become widespread threats. In this episode of Science Changing Life , project scientist Josh Levy and PhD student Praneeth Gangavarapu explain how analyzing what goes down the drain can offer life-saving insights into the future of public health. Learn more about the role of wastewater surveillance in tracking a range of viruses—including SARS-CoV-2, H5N1 and even seasonal influenza. // Bluesky: https://bsky.app/profile/josh-levy.bsky.social, https://bsky.app/profile/praneethg.bsky.social Andersen lab: https://andersen-lab.com/ Scripps Research Magazine: magazine.scripps.edu/…

Science Changing Life

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Virologist gives update on H5N1, mpox, and preparing for an uncertain future 31:40

hace 5 weeks31:40

31:40

Roughly two years ago, virology expert and Scripps Research professor Sumit Chanda sat down with Science Changing Life to discuss all things pandemic preparedness and COVID-19. But the world is in a very different place now, with infectious disease threats like H5N1, mpox and Dengue virus on the rise. Chanda joins us once again to share the latest in the virology space, how scientists can be better communicators, and his advice for making sure we’re as prepared for an uncertain future as we can be. Instagram: instagram.com/thechandalab/ Chanda lab: chandalab.org/ Twitter/X: x.com/thechandalab Scripps Research Magazine: magazine.scripps.edu/…

Science Changing Life

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The long haul: Personal and scientific insights into long COVID 24:49

hace 10 weeks24:49

24:49

Long COVID affects millions of people worldwide, yet many questions about the condition remain unanswered. In this episode of Science Changing Life, Julia Moore Vogel, PhD, shares what it’s like to study—and live with—long COVID. As the senior director of the All of Us Research Program, Julia discusses how her experience has fueled innovative research to improve symptom management and health equity for patients with the condition. Listen in to learn how Julia transforms personal challenges into professional breakthroughs. Twitter: https://x.com/julialmv LinkedIn: https://www.linkedin.com/in/juliamoorevogel All of Us Research Program: https://www.joinallofus.org/ Scripps Research Magazine: magazine.scripps.edu/…

Science Changing Life

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Futureproof: Eric Topol on revolutionizing pandemic preparedness 10:52

hace 17 weeks10:52

10:52

In the second part of our conversation with Dr. Eric Topol, we explore how examining the past is necessary to ensure we’re more prepared for our future. From universal vaccines and advanced antiviral therapies to cutting-edge digital tools like wearable biosensors and genomic surveillance, Dr. Topol shares actionable insights on harnessing technology and data to revolutionize pandemic preparedness. Listen in as we discuss the path to a safer, healthier future. // Episode transcript: https://www.scripps.edu/_files/images/2024_images/topol-pandemic-prep-transcript.pdf Twitter: https://twitter.com/EricTopol LinkedIn: https://www.linkedin.com/in/eric-topol-md-b83a7317/ Ground Truths podcast: erictopol.substack.com Scripps Research Magazine: magazine.scripps.edu/…

Science Changing Life

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Beyond the hype: AI’s impact on medicine and science with Eric Topol 40:00

hace 21 weeks40:00

40:00

Artificial intelligence is revolutionizing what we once thought impossible. But how can we distinguish genuine breakthroughs from mere hype? In this episode of Science Changing Life, we welcome Eric Topol, MD—renowned physician, scientist, and author. As executive vice president at Scripps Research and founder of the Scripps Research Translational Institute, Dr. Topol shares his thoughts on how AI is transforming science and medicine today and offers a glimpse into what the future may hold. His advice to listeners? 'Be open to change.' Twitter: https://twitter.com/EricTopol LinkedIn: https://www.linkedin.com/in/eric-topol-md-b83a7317/ Ground Truths podcast: erictopol.substack.com Scripps Research Magazine: magazine.scripps.edu/…

Science Changing Life

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Gene editing, CRISPR, and drawing the line between science and fiction 39:33

hace 26 weeks39:33

39:33

Thanks to revolutionary technologies like CRISPR, we’re now living in an age where it’s becoming possible to rewrite the very building blocks of life itself—our DNA. We sit down with Scripps Research Fellow and CRISPR expert Shannon Miller, PhD, to discover how these gene editing technologies are poised to reverse a range of diseases. Listen in as we explore Shannon’s unique journey into science—beginning not with a single eureka moment, but instead with a passion for creativity and discovery. Twitter: https://twitter.com/_shannonmmiller Miller lab: https://www.millerlabresearch.com/team Scripps Research Magazine: https://magazine.scripps.edu/…

Science Changing Life

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Everything we know about H5N1 bird flu 27:54

hace 34 weeks27:54

27:54

Four years after the onset of the COVID-19 pandemic, another virus threatens to reach pandemic potential: the H5N1 bird flu. We sit down with Arnab Chatterjee, vice president of medicinal chemistry at Calibr-Skaggs, who explains the need to invest in the best science to make sure we’re more prepared than we were for the SARS-CoV-2 outbreak. Chatterjee breaks down how likely it is for H5N1 to become transmitted between humans, and the steps we can take now to better protect ourselves in the future. LinkedIn: linkedin.com/in/arnab-chatterjee-b024661/ Scripps Research Magazine: magazine.scripps.edu/…

Science Changing Life

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Building a 'telescope' for the brain 27:40

hace 40 weeks27:40

27:40

Galileo’s telescope revolutionized our modern understanding of the universe. Assistant neuroscience professor Xin Jin, PhD, wants to do just that—except for the brain. By building new tools that enable her and other neuroscientists to peer into the inner workings of the mind, Jin is uncovering the cells, genes and other complex drivers behind neurological diseases. Listen in as we explore the galaxy of the brain. Twitter: https://x.com/xinjin Jin lab: https://www.jin.scripps.edu/ Scripps Research Magazine: magazine.scripps.edu/…

Science Changing Life

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A physician-scientist’s guide to developing medicines 30:30

hace 45 weeks30:30

30:30

More than 90% of drugs fail to make it from the lab bench to approval. How, then, has a physician-scientist like Hugh Rosen found so much success in developing medicines? Rosen, who’s the chair of molecular and cellular biology at Scripps Research, co-invented the drugs ozanimod (approved for multiple sclerosis and ulcerative colitis) and navacaprant (in Phase 3 trials for major depressive disorder). In this episode of Science Changing Life, listen in as Rosen unveils the success stories behind these groundbreaking treatments—shedding light on the challenges and triumphs shaping modern medicine. Rosen Lab: https://www.scripps.edu/rosen/index.html Scripps Research Magazine: magazine.scripps.edu/…

Science Changing Life

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Solving the origins of life and other mysteries in chemistry 37:34

hace 49 weeks37:34

37:34

Donna Blackmond never thought her career would lead to solving how life first formed on the prebiotic Earth. But as she points out in this episode of Science Changing Life, does any scientist start out knowing where their research will take them? Blackmond, who is a professor and the John C. Martin Endowed Chair in Chemistry at Scripps Research, shares how her wide-ranging background across chemistry and chemical engineering is helping answer some of today’s biggest questions in science and medicine. Episode transcript: https://www.scripps.edu/_files/images/2024_images/donna-blackmond-podcast-episode-45-transcript.pdf Blackmond Lab: https://www.scripps.edu/blackmond/ Blackmond’s recent PNAS and Nature papers: https://www.scripps.edu/news-and-events/press-room/2024/20240228-blackmond-molecules.html Scripps Research centennial: 100.scripps.edu/ Scripps Research Magazine: magazine.scripps.edu/…

Science Changing Life

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How biosensors are enabling a new era in medicine 30:10

hace 1 year30:10

30:10

Dr. Jay Pandit is a director of digital medicine at the Scripps Research Translational Institute and an assistant professor in the Department of Molecular Medicine at Scripps Research, where he combines medicine and technology to improve patients’ clinical outcomes. Listen in as we explore how biosensors and wearable technologies are enabling users to take control of their own health data and usher in a new era of personalized medicine. Episode transcript: https://www.scripps.edu/_files/images/2024_images/jay-pandit-transcript.pdf X: https://twitter.com/JayPandit LinkedIn: www.linkedin.com/in/jay-pandit-9489008 Scripps Research centennial: https://100.scripps.edu/ Scripps Research Magazine: https://magazine.scripps.edu/…

Science Changing Life

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Episode 43 – Ahmed Badran: Bioengineering our way out of climate change 31:00

hace 2 years31:00

31:00

Ahmed Badran is an assistant professor of chemistry at Scripps Research, where his lab harnesses synthetic biology to address some of biggest global problems. Listen in as we discuss reengineering plant enzymes to capture carbon, plastic-eating bacteria and new classes of antibiotics that spare our gut microbiome. Episode transcript: https://www.scripps.edu/_files/images/2023_images/ahmed-badran-transcript.pdf Badran lab website https://badranlab.com/ Twitter @AhmedHBadran Scripps Research Magazine https://magazine.scripps.edu/…

Science Changing Life

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Episode 42 – Mia Huang: How sugar biology can help diagnose and treat cancer 19:45

hace 2 years19:45

19:45

Professor Mia Huang is based in the Department of Molecular Medicine at Scripps Research, where her lab explores how vital sugar molecules in the body orchestrate complex biological events. Listen in as we discuss deciphering cancer cell signals to develop new therapies, engineering red blood cells for transfusions and how to become a master of strategy. Episode transcript: https://www.scripps.edu/_files/images/2023_images/mia-huang-transcript.pdf Huang lab website https://www.huangresearch.com/ Q&A with Mia https://magazine.scripps.edu/profiles/2020/fall/science-with-a-view-understanding-how-natures-biomolecules-tick-with-mia-huang/ Twitter @HuangMia Scripps Research Magazine https://magazine.scripps.edu/…

Science Changing Life

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Episode 41 – Ram Krishnamurthy: Astrobiology, origins of life and the search for extraterrestrials 22:57

hace 2 years22:57

22:57

Professor Ram Krishnamurthy is based in the Department of Chemistry at Scripps Research, where his lab investigates the reactions that could have first given way to life on Earth. Listen as we discuss finding biological building blocks on meteorites, NASA’s search for life on other planets, and staying grounded with philosophy and meditation. Episode transcript https://www.scripps.edu/_files/images/2023_images/ram-krishnamurthy-transcript.pdf Ram’s faculty profile https://www.scripps.edu/faculty/krishnamurthy/ Astrobiology at NASA https://astrobiology.nasa.gov/news/new-nasa-research-consortium-to-tackle-lifes-origins/ Scripps Research Magazine https://magazine.scripps.edu/…

Science Changing Life

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Episode 40 – Sumit Chanda: How can we prepare for the next pandemic? 31:39

hace 2 years31:39