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Episode 17: On-demand Control of Endogenous Genes
Manage episode 319300132 series 2942968
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This week we discuss an amazing new technique developed by Dr Jakub Gemperle (@GemperleJakub), a Marie Curie Postdoctoral Research Fellow at the University of Manchester (@OfficialUoM). This technique uses 3 different inducible systems to allow on-demand control of endogenous genes, including being able to remove genes and then re-express them. A nice all in one package of techniques, great for rescue experiments!! We then also talk about Magnetogenetics where cells (and vesicles) can be moved around via magnets! As always we ask how this person found preprinting and we delve into the wonderful idea of permanent postdocs.
Read the full preprint: https://www.biorxiv.org/content/10.1101/2021.12.03.471086v1.full
Other links
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001285
First Pig to Human heart transplant
https://www.nature.com/articles/d41586-022-00111-9
This episode was produced by Emma Wilson and edited by John D Howard.
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