CREATING A NEW HEALTH GENERATION WITH PREVENTION AND LONGEVITY MEDICINE

Alloutcoach

What a better way to start the new 2024 year than to learn about the current, realistic prospect of living longer and better lives due to the latest advances in medicine and pharmaceutical research from a preventive and longevity medicine advocate, researcher, and expert, James Peyer, PhD. This episode features a personal, candid story of his journey from academia into the industry, inspiration behind pursuing preventive healthcare and longevity treatments, and latest new treatments in human trials that increase healthspan and lifespan from a keynote speech at the 2nd annual global Medical Affairs Innovation Olympics Opening Ceremony in 2023. Subscribe to Alloutcoach and share this episode with your friends! 0:00 Episode Introduction 5:10 James Peyer's Keynote Speech Outline 7:14 James Peyer's late grandfather and inspiration to pursue prevention medicine 7:55 Frustration with Health System's Interaction with Elderly 9:53 Early animal experiments in genes doubling lifespan 11:14 80+ treatments that extend healthy lifespan in animal models today 13:09 Real-world reason why human trials in slowing aging did not advance 14:10 Breakthrough Idea to Advance Prevention Medicine in Humans 16:35 Cambrian Bio's unique Longevity Platform Ecosystem 19:42 Two Longevity Medicine Biotech Case Studies 20:50 Amplifier Therapeutics - a Cambrian Bio Pipeline Company 23:48 New Promise in 10-year race to develop an AMPK (central energy regulator) activator 25:40 ATX-304: new AMPK candidate in human trials 27:50 Second Vignette: Velakor - agrin-induced pleiotropic cardiac repair 31:11 Velakor's Agrin in human clincal trials in 2024 to regenerate heart muscle 33:25 Q1: Regulatory approval considerations for other longevity medicine companies 34:08 Conduct Primary and Secondary Prevention Trials - FDA supportive of preventive treatments 35:21 FDA interested in preventive medicine, transition from sick care to preventive care in US 37:11 Q2: Difference between healthspan and lifespan, and impact on drug development 38:22 Patient Survey Data on Critical Value of Quality not only Length of Life 41:25 Q3: Technological innovations most promising in increasing longevity and healthspan 43:49 James' Final Message on Innovation and Entrepreneurship