Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
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Insightful conversations with leading experts in the field of health care, medical research, policy, and more from the New England Journal of Medicine (NEJM). Each episode examines the many complexities found at the junction of medicine and society.
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NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You’ll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations w ...
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Audio podcasts featuring the week’s top medical news plus pertinent interviews
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The House reflects medicine’s most pressing issues through the eyes of residents, providing a forum to share their stories from the bedside, where they are learning far more than the lessons of clinical medicine.
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A Day in the Life is a podcast for medical students, by medical students. Interviews with attendings about daily life and training may help you explore a range of specialties.
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NEJM Interview: Alex Keuroghlian on responding to policy threats to protections for transgender and nonbinary people.
9:58
Alex Keuroghlian is an associate professor of psychiatry at Harvard Medical School and the director of the Division of Public and Community Psychiatry at Massachusetts General Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.R.A. Coelho, A.L. Chen, and A.S. Keuroghlian. Advancing Transgender Health am…
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Featuring articles on breast cancer, bloodstream infection, subarachnoid hemorrhage, scrub typhus, and birth-related mortality; a review article on the evaluation and treatment of infertility; a case report of a woman with altered mental status and acidemia; and Perspectives on advancing transgender health amid policy threats, on evidence-based wor…
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From Clinical Notes to GPT-4: Dr. Emily Alsentzer on Natural Language Processing in Medicine
55:06
Dr. Emily Alsentzer joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds to discuss the evolution of natural language processing (NLP) in medicine. A Stanford faculty member and expert in clinical AI, Emily shares her journey from pre-med to biomedical AI, the role of language models in medical decision-making, and the ethical consideration…
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In this audio interview, Editor-in-Chief Eric Rubin and Deputy Editor Lindsey Baden are joined by state public health leaders Robbie Goldstein and Jennifer Shuford to discuss action against H5N1 in Massachusetts and Texas and across the nation. Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Robert…
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NEJM Interview: Sara Gerke on the potential for genetic data and other personal information to be included in business transactions in the United States.
7:00
Sara Gerkeis an associate professor of law at the University of Illinois Urbana-Champaign. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S. Gerke, M.B. Jacoby, and I.G. Cohen. Bankruptcy, Genetic Information, and Privacy — Selling Personal Information. N Engl J Med 2025;392:937-939.…
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Featuring articles on bacterial vaginosis, diabetes prevention, Danon disease, chronic spontaneous urticaria, and VITT-like monoclonal gammopathy of thrombotic significance; a review article on micronutrients; a Clinical Problem-Solving on unveiling the unforeseen; and Perspectives on bankruptcy and genetic information, on drug development for rare…
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In this NEJM Outbreaks Update, Editor-in-Chief Eric Rubin and Deputy Editor Lindsey Baden are joined by veterinarian and virologist Yoshihiro Kawaoka to discuss avian influenza and its current impact on chickens, cows, cats, and humans. Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Yoshihiro Kawa…
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John Kelly is the director of the Recovery Research Institute at Massachusetts General Hospital and a professor of psychiatry in addiction medicine at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.F. Kelly, N.D. Volkow, and H.K. Koh. The Changing Approach to Addiction — From Incarcera…
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Featuring articles on H5N1 infection, chronic subdural hematoma, achondroplasia, and B-cell acute lymphoblastic leukemia; a review article on carceral health care; a case report of a woman with weakness, back pain, and pancytopenia; and Perspectives on the changing approach to addiction, on the moral injury of inhaler prescribing, and on how one si…
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NEJM Interview: Peter Ubel on strategies for protecting patients from high out-of-pocket costs for drugs with questionable benefits.
6:55
Peter Ubel is a professor of business, public policy, and medicine at Duke University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. P.A. Ubel, A. Grouls, and A.S. Kesselheim. Out of Pocket Getting Out of Hand — Reducing the Financial Toxicity of Rapidly Approved Drugs. N Engl J Med 2025;392:729-731.…
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Featuring articles on ventricular tachycardia, chronic lymphocytic leukemia, chronic kidney disease, kidney allografts, and a low-dose yellow fever vaccine; a review article on tubal ectopic pregnancy; a case report of a man with abdominal pain; and Perspectives on reducing the financial toxicity of rapidly approved drugs, on resilience, and on the…
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NEJM Interview: Yashaswini Singh on the expansion of private equity investments in health care and actions to safeguard patient interests in various countries.
11:58
Yashaswini Singh is an assistant professor of health services, policy, and practice at Brown University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. Y. Singh, E. Fuse Brown, and I. Papanicolas. The Rise of Private Equity in Health Care — Not a Uniquely American Phenomenon. N Engl J Med 2025;392:627-629.…
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Featuring articles on therapies in acute myocardial infarction and in neuroendocrine tumors, mpox in Africa, and T-cell lymphoma after CAR T-cell therapy; a review article on food and nutrition insecurity; a case report of a woman with headache and dysesthesia; and Perspectives on Marburg virus disease in Rwanda, on the rise of private equity in he…
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Joseph Ross is a professor in the Department of Internal Medicine at the Yale School of Medicine and in the Department of Health Policy and Management at the Yale School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.S. Ross. Cell and Gene Therapies — Improving Access and Outcomes for Medica…
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Featuring articles on IgA nephropathy, a treatment in children with obesity, NRG1 fusion–positive cancer, a case of a T-cell lymphoma, and the discovery of GLP-1–based drugs; a review article on hemophagocytic lymphohistiocytosis, a Clinical Problem-Solving on traveling companions; and Perspectives on cell and gene therapies, on gender-affirming ca…
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NEJM Interview: Daniel Aaron on a Supreme Court case about e-cigarettes that could have implications for the FDA’s authority and for public health.
9:22
Daniel Aaron is an associate professor of law at the University of Utah S.J. Quinney College of Law. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.G. Aaron and C. Robertson. E-Cigarettes at the Supreme Court — Potential Implications for the FDA and Public Health. N Engl J Med 2025;392:417-419.…
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Featuring articles on heart failure and obesity, oral anticoagulation during TAVI, hemophilia A, hereditary angioedema, and tuberculosis; a review article on sport-related concussion; a case report of a man with syncope, ankle swelling, and abnormal chest imaging; and Perspectives on e-cigarettes at the Supreme Court, on providing interstate telehe…
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NEJM Interview: Craig Spencer on the need for action to address persistent inequities in global health.
17:34
Craig Spencer is an emergency medicine physician and an associate professor of the practice of health services, policy, and practice at the Brown University School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. C. Spencer. Ebola and a Decade of Disparities — Forging a Future for Global Health …
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Featuring articles on esophageal cancer, out-of-hospital cardiac arrest, and atrial fibrillation; a review article on the physiology of hunger; a case report of a man with exertional dyspnea and chest pain; a Medicine and Society on evaluating the inclusion of sex in clinical algorithms; and Perspectives on Ebola, on U.S. generic drug shortages, on…
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NEJM Interview: Carmel Shachar on modernizing labor laws and strike regulations to support physicians, patients, and hospitals.
9:16
Carmel Shachar is an assistant clinical professor of law and faculty director of the Health Law and Policy Clinic at Harvard Law School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. T. Ramesh, C. Shachar, and H. Yu. Striking a Balance — Advancing Physician Collective-Bargaining Rights and Patient Protections.…
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Featuring articles on asymptomatic severe aortic stenosis, kidney disease, fracture prevention in women, and residual breast cancer, the future of the U.S. physician workforce, mutant KRAS signaling, and manufactured chemicals and children’s health; a review article on the identification and treatment of alcohol use disorder; a case report of a man…
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Health Care at the Breaking Point: Dr. Zak Kohane Returns to NEJM AI Grand Rounds
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1:08:28In this return appearance on NEJM AI Grand Rounds, Dr. Zak Kohane joins hosts Raj Manrai and Andy Beam to discuss the evolving landscape of AI in medicine. As the first repeat guest on the show, Dr. Kohane shares insights on health care system challenges, the Human Values Project, and his perspectives on the most significant AI developments of 2024…
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NEJM Interview: David Velasquez on care for older, low-income adults who can’t enroll in Medicare or Medicaid because they’re undocumented immigrants.
11:35
David Velasquez is an internal medicine resident physician at Brigham and Women's Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.E. Velasquez, E.T. Roberts, and J.F. Figueroa. The Plight of “Dual Noneligible” People in the United States. N Engl J Med 2025;392:105-107.…
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Featuring articles on transcatheter tricuspid-valve replacement, persistent chylomicronemia, multiple myeloma, myelofibrosis, and peripherally inserted central catheter materials; a review article on heart failure with preserved ejection fraction; a case report of a woman with shortness of breath and leg edema; and Perspectives on the plight of “du…
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NEJM Interview: Joey Mattingly on providing widespread access to HCV treatment at the lowest possible price.
12:16
Joey Mattingly is an associate professor in the Department of Pharmacotherapy at the University of Utah College of Pharmacy. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S.S. Tu, S. Kottilil, and T.J. Mattingly II. Leveraging Old Hepatitis C Therapies. N Engl J Med 2025;392:1-4.…
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Featuring articles on advanced melanoma, atrial fibrillation, ATTR amyloidosis, and bladder cancer; a review article on cervical cancer; a Clinical Problem-Solving describing when blurry vision clouds the bigger picture; Medicine and Society’s on transitional justice and on rethinking access to HIV medicines; and Perspectives on hepatitis C therapi…
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