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The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
 
16 Minutes on the News is a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends? About the a16z Podcast: Discusses tech and culture trends, news, and the future -- especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This ...
 
Conversations on Clubhouse and beyond -- to capture and share many of the live discussions and events featuring, hosted, or co-hosted by a16z partners (with outside voices too). Many of these different discussions and events take place on the social audio/ drop-in chat app Clubhouse; to attend those in real time or sign up for the app please visit joinclubhouse.com. As a reminder, all content posted here is provided for informational purposes only, and should not be relied upon as legal, bus ...
 
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show series
 
This conversation centers on the arguments and findings of the a16z piece The Cost of Cloud, a Trillion Dollar Paradox. The Core Findings of The Cost of Cloud piece [5:22] Cloud is a significant part of COGS for public SaaS companies [8:38] Should you allocate engineers to reduce cloud cost or just focus on growth? [12:06] How much of a problem is …
 
Given recent news of drug company settlements, calls to action, policy moves, and more, this episode is a rerun of one of our very early explainers (episode #4 of 16 Minutes, 2019) on the opioid crisis. Bio experts and a16z general partners Jorge Conde and Vijay Pande discuss on 16 Minutes (our shortform show where we discuss the headlines, tease a…
 
There's been a false dichotomy in technology and management lore over the past decade, between "brain" and "brawn", digital and physical, independence and interdependence, software culture versus industrial culture… or so observes Stanford Graduate School of Business lecturer, former big-company executive, and startup founder Robert Siegel in his n…
 
This podcast is an excerpt. Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full. Early days of a16z crypto [2:38] New crypto governance capabilities [16:34] How is the VC model different when investing in crypto? [22:24] Crypto regulation and the recent attempt at holiday rulemaking [29:49] Is anyon…
 
What makes a category? [0:37] The leading indicator? Everyone thinks you're crazy. [5:36] Can you create a category whole cloth? [7:02] How to create a category [12:05] The best category creation CEOs are product marketers [15:55] Category creation tactics: certification programs [18:54] Category creation tactics: persona-based storytelling [22:17]…
 
SPEAKERS (in order they are heard in the episode): Shannon Kelly, a16z Connie Chan, a16z Brandon Chu, VP Product and GM of Platform, Shopify D'Arcy Coolican, a16z Nait Jones, a16z Jess Lee, Cofounder and CEO, Modern Citizen Imran Khan, Co-founder and CEO, Verishop This is an excerpt from the a16z Clubhouse show People Behind the Product. To catch f…
 
The origins of growth hacking [1:20] Brand building vs. growth hacking? [13:58] Where does growth fit into the organization? [31:06] The cold start problem: growth hacking from 0 to 1 [36:47] What can't be measured? [47:53] How do you test and validate new channels? [51:38] Do growth hacks always work, or at some point does it come down to product?…
 
Why Future with Marc Andreessen, Margit Wennmachers, and Sonal Chokshi [2:20] The New Creator Economy with Joost van Dreunen, Wes Kao, Cuy Sheffield, Chris Lyons, Lauren Murrow, and Zoran Basich [17:58] Bubbles, Speculation, and Innovation with Byrne Hobart, Jamie Catherwood, and Zoran Basich [35:38] Work Models & Measures for the Information Age w…
 
What was the biggest surprise from the past 15 months of remote work? [5:24] How do you handle conflict and build trust? [10:09] What's the role of offsites? [15:45] Should you adjust compensation for different geographies? [24:02] How do you measure productivity? [34:10] What is the impact of remote work on retention and turnover? [49:17] How do s…
 
This podcast is an excerpt. Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full. In this episode: The abandoned M&A with Visa [3:47] Communicating to employees around the M&A [8:29] Plaid's near death experiences in the early days [12:41] The fintech trends that made Plaid possible [17:29] What is a…
 
In what ways is digital health for complex care under or overrated? [4:04] Are digital health solutions better suited to tackling clinical or non-clinical needs for complex care? [17:32] The challenge of the physician's inbox [27:55] Have we meaningfully moved the needle on complex digital care? If so, where? [32:08] Should we focus on applying bas…
 
Decentralized autonomous organizations, or DAOs, are one of the hottest topics in crypto and tech right now. But what exactly are they? Why do they matter? And what new modes of governance, ownership, and creation do they make possible?Por Aarthi Ramamurthy, Will Papper, Avichal Garg, Ali Yahya, pplpleasr, Sriram Krishnan, Ian Lee, Steven Sinofsky, Denis Nazarov
 
mRNA research before COVID and how "mRNA is code" [3:21] The early days of COVID: designing a vaccine in 48 hours [5:44] The software behind the vaccine: getting mRNA researchers out of Excel and into a drug design studio [9:11] The first draft of the vaccine was the final draft [11:10] How the government sped up vaccine development for COVID [12:1…
 
Welcome to 16 Minutes, the a16z show where we talk about tech trends in the news, what’s hype and what’s real, and the long arc of innovation. In today's episode we’re talking about the latest developments and trends in cybercrime – including the trends of ransomware, and, attacks on physical infrastructure. First (0:00 - 6:07), we have the recent …
 
Fab 5 Freddy on New York in the 70s, Warhol, Blondie, Basquiat, and Yo! MTV Raps [1:40] Contrarian strategy and challenging assumptions [5:12] Boring AI and solving meaningful problems [8:42] Drop-in audio copycats [14:39] How is copying software different from remixing hip hop? [21:07] Do you want a CEO as an inventor or an operator? [24:12] Recru…
 
Given recent buzz and ongoing debates around the Endless Frontiers Act -- which some have described as “the most important piece of legislation no one's heard of” -- this episode is a rerun of an episode from last year, recorded after said act was initially unveiled. The short discussion covers the broader topic and theme of funding science and inn…
 
The six functions in an enterprise marketing org [2:54] Why product marketing is the killer function [6:52] How do you hire a world class product marketer? [11:16] Is community or developer evangelists its own function or part of product marketing? [17:46] How does community tie into the marketing funnel? [22:56] Is community top of funnel, an acce…
 
What did Substack think about the NYTimes article "Why We’re Freaking Out About Substack" [1:01] What is Substack? [4:40] The issues with social media content models and how Substack is different [5:54] What about the echo chamber? [8:54] Turning cultural principles (e.g., freedom of the press) into actual culture [12:00] Will Substack replace trad…
 
eBay to today, a brief history of collectibles and tech [1:03] Are collectibles about sentiment or investment? [5:13] How do you bring the excitement of a collection to digital goods? [13:34] Is the future of all collectibles digital? [20:20] The role of blockchain and NFTs [26:39] Are collectible marketplaces different from other marketplaces? [32…
 
Recently, a16z and the Stanford Center for Blockchain Research hosted the NFT Virtual Summit, which brought together leading thinkers and builders on the topic of NFTs, or non-fungible tokens — these tokens are enabling new creator and ownership economies to emerge. We’ve covered NFTs in other podcasts and articles, including a curated list of read…
 
For videos of the NFT Virtual Summit, visit a16z.com. Session 1: The Future of the Digital Ownership Economy with Dan Boneh (Stanford University) and Chris Dixon (a16z) What is an NFT? [3:01] Why are NFTs so big right now? [7:04] The most exciting programmable ownership structures [11:36] NFTs and composability: what can you do with NFTs? [15:16] H…
 
What inspired Eric and Sam to start Dyno [4:09] How does the use of ML impact Dyno's GTM [10:40] The current challenges of gene therapy [21:43] Why Dyno wants to be a horizontal platform for gene therapy [30:56] How does Dyno think about competition [44:23] After party and audience Q&A [52:01] It's Time to Heal, Mondays at 5pm PT on Clubhouse. Join…
 
Note: the recording of this episode starts a minute or two into the show. Ali recommends: The Hard Thing about Hard Things by Ben Horowitz [0:18] Ben recommends: High Output Management by Andy Grove [4:36] Marc recommends: Who Really Matters: The Core Group Theory of Power, Privilege, and Success by Art Kleiner [10:48] Best read for enterprise sale…
 
How Ben took over Take Two [1:42] How digital distribution and publishing changed gaming [8:36] What is a next generation publisher? [13:51] Can publishers add value as tastemakers? [17:36] How do you make sure studios ship on time? And in the era of persistent game worlds, does it matter? [22:01] Lessons learned from Take Two [27:27] Taking the lo…
 
Robert's foundational experiences growing up [3:03] His introduction to computers, how he got an internship at Bell Labs, and what he learned there [6:38] Why he studied chemical engineering [13:15] Working at Kraft and engineering macaroni and cheese [15:08] Why he moved to investing [18:12] How he realized that it made sense to do buyouts in ente…
 
What happened at Basecamp and could it have gone differently? [3:51] When did Basecamp turn into a 4B? [7:45] Why were buyouts a good policy for Basecamp and Coinbase? [10:26] Why not have a more moderate policy? [11:56] What makes something "political"? [14:45] What about when political issues have a personal impact on employees? [19:18] What happ…
 
What are red teams and blue teams? [2:03] How Cedric cracked Mac Gatekeeper [6:55] Apple's response [15:22] Cedric's craziest hack [19:24] Red team advice for the blue team [22:02] Audience Q&A [26:31] 🔐Breach of the Week 🔐looks at who got hacked, how it happened, and what it means for the industry. 🎙With hosts Joel de la Garza (a16z Security Opera…
 
On this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Julie Yoo, Vijay Pande, and Jorge Conde talk to guest Shantanu Nundy, the Chief Medical Officer of Accolade. The conversation covers Dr. Nundy's new book, "Care After Covid: What the Pandemic Revealed Is Broken in Healthcare and How to Reinvent It", the next ste…
 
Why does it feel like there's a database for everything? [4:46] What is the actual use case and market for streaming? [9:34] How real is real time? [20:12] Can you do everything in SQL? [25:08] Is the future SQL extensions or does SQL become embedded in data frames? [40:19] Is database consolidation coming? How many different systems will we have? …
 
What is AI? [2:27] AI is statistics, not consciousness [7:05] Why then so much talk about the singularity? [12:12] AI breakthroughs and FAANGs [17:21] Building the AI toolchain [26:07] AI applications in bio and medicine [30:19] Ali's favorite AI use cases [34:35] What will AI do to jobs? [39:27] AI in 10 years [46:09] Snowflake, Databricks, data L…
 
In this episode: Melody McCloskey - CEO of StyleSeat, a booking platform that connects stylists and beauty professionals with clients. Since its founding in 2011, StyleSeat has powered 150 million beauty appointments and generated over $6.5 billion in revenue for beauty professionals. The company has created a loyal community of the country’s leadi…
 
On this episode of the a16z Bio Clubhouse Show, a16z general partners Julie Yoo and Jorge Conde, managing partner Scott Kupor, and market development partner Venkat Mocherla talk to guest Florian Otto, cofounder and CEO of Cedar. The conversation covers how to improve two of the trickiest aspect of healthcare: price transparency and patient engagem…
 
Playing out against the backdrop of a global pandemic (including recent massive surges in regions around the world) is the news that came out a week ago that a candidate "malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal”. While the findings are still in preprint with The Lancet, the resulting buzz and phrases quoted included…
 
Playing out against the backdrop of a global pandemic (including recent massive surges in regions around the world) is the news that came out a week ago that a candidate "malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal”. While the findings are still in preprint with The Lancet, the resulting buzz and phrases quoted included…
 
Inside sales, field sales, product-led, channel sales, marketing, post-sales… a16z GTM is our clubhouse show for enterprise founders and builders about what it takes to go to market and the evolving strategies and lessons learned from enterprise companies past and present. Every other Thursday 4-5pm with David Ulevitch. For our upcoming schedule of…
 
a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more live on Clubhouse Mondays at 7pm PT. In this conversation: Which institution will last longer Harvard or the US? [00:58] How do you craft a good culture in a high pressure environment? [13:45] When will we have AGI? [31:15] Are network effec…
 
In this episode: Jim Messina - CEO, The Messina Group; formerly Obama's Deputy Chief of Staff; known as the "fixer" and "the most powerful person in Washington you've never heard of" Adrian Durbin - currently at Greenbrier; former Director of Policy Comms at Lyft Risa Heller - CEO of Risa Heller Communications; former Director of Comms for Senator …
 
On this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Julie Yoo, and Jorge Conde talk to guests Sean Duffy, cofounder and CEO of Omada Health, Karan Singh, cofounder and COO of Ginger, and Chris Hogg, a serial entrepreneur in the digital health space. The conversation covers go-to-market strategies, financing and a…
 
In this episode: Jamie Byrne, Senior Director of Creator Partnerships, YouTube Shishir Mehrotra, former Director of Product Management, YouTube; former VP of Product, Engineering, UX, YouTube; current Founder & CEO, Coda Shiva Rajaraman, former Director, Product Management (etc.); current VP Shops and Business, Facebook Lauren Riihimimaki (aka Laur…
 
In this week’s episode of 16 Minutes, our show where we cover tech trends in the news — and also cover themes from company developer and innovation events! — we focus on the latest coming out of Apple’s event this week. The company announced a bunch of things, ranging from new device colors and form factors to podcast services, but in this episode …
 
a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more live on Clubhouse Mondays at 7pm PT. In this conversation: NFTs and tokenization — how will they impact the arts, media, music and investing strategies? The potential for DeFi Using shocking new rules to create culture Structuring options to…
 
a16z Infra is the Clubhouse Show where the a16z enterprise team and guests discuss the foundational technology and products that underpin all of tech. We dig deep into data, AI/ML, security, developer tools, compute, network, storage, hardware, and anything else found below the surface of modern stacks. Like what you hear? Tune in for our next show…
 
On this episode of the a16z Bio Clubhouse Show, a16z general partners Vineeta Agarwala, Julie Yoo, and Jorge Conde talk to guest Connie Chen, Chief Medical Officer at Lyra health. The conversation covers what makes digital health different from traditional healthcare delivery, how to build a sustainable business model while maintaining high standar…
 
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